Konami's Pro Evolution Soccer 6, last week's number one, sits behind at number two in the charts, with FIFA 07 and The Sims 2: Pets at number three and four, respectively.

Rockstar's Canis Canem Edit fails to climb the charts, staying at number five, while the publisher's PSP title Grand Theft Auto: Vice City Stories makes its debut at number six.

Falling down the charts are Sega's Football Manager 2007 at number seven and Tom Clancy's Splinter Cell: Double Agent at eight.

The only other new entry in the top ten is THQ's expansion pack Warhammer 40,000: Dawn of War Dark Crusade at number nine, which sits ahead of VU Games' Scarface: The World is Yours at ten.

Mayo Clinic Cancer Center Prostate SPORE Grant Renewed

Mayo Clinic Cancer Center's Specialized Programs of Research Excellence (SPORE) grant from the National Cancer Institute (NCI) for prostate cancer research has been renewed for an additional five years. SPORE grants are highly competitive awards given to institutions on the cutting edge of translational research in specific types of cancer.

Mayo's original five-year prostate SPORE grant of $12 million was awarded in 2001. The current grant brings an additional $11.2 million over five years to Mayo Clinic to advance translational research intended to reduce deaths due to prostate cancer. Mayo Clinic oncology researcher Donald Tindall, Ph.D. is the principal investigator. He leads a large multidisciplinary team of basic, clinical and population science investigators in translational research projects to help prostate cancer patients and those at risk for prostate cancer.

The prey becomes the hunter in Rankin's forceful 'Bleeding Heart'

A paid assassin killing time before his next hit shares a drink in a bar with a businessman as the conversation ironically turns to bleeding hearts. No room for bleeding hearts, the killer comments, then notes wryly to himself that bleeding hearts are the business.

British author Ian Rankin is back with yet another forceful, muscular novel, and the result is a gritty thriller in which the killer is more likable than his hunter, an obese, pill-popping, cocaine-sniffing New York private investigator named Leo Hoffer.

Lenovo sets sights on home PC market

The market for home computing is booming, and companies like Lenovo, already well-keeled in business PCs are keen to get a piece of the pie, opening up to 700 store fronts across the Asia Pacific with the target squarely set on consumers, offering both the hardware and software that they'd find attractive. By December, there will be a new range of consumer desktops (the Lenovo Q and H series) and laptops (the Y300 and Y400), catering to the growing number of high tech homes and families in Singapore, Malaysia, Thailand and Indonesia. The numbers are hard to ignore, in Singapore some 46 per cent of total PC sales come from the consumer market, while in Malaysia the number is just over 20 per cent of the total PC market. Market growth is also staggering, it's more than 50 per cent for Indonesia and in Thailand that number is about 35 per cent.

Double Agent Puzzle Cube Guide

This strategy guide will help you get past one of the hardest parts in Tom Clancy's Splinter Cell: Double Agent, the puzzle cube. You'll be faced with it at the start of the New York City JBA Headquarters Part 3 mission. After the mission begins, follow Emile downstairs and he will eventually lead you to a computer. He will then ask you to decrypt an email for him, which is when you'll have to figure out the incredibly complicated puzzle cube. You'll have a limited amount of time to crack the puzzle, so work fast and look over our guide which will help you make sense of the puzzle cube.

1UP.com Gives Away a Nintendo Wii(TM) Every Day in December

1UP.com is the community and editorial hub of the 1UP Network, the leading integrated media network for gamers. The site is hosting a series of special features and contests to celebrate the 2006 holiday gaming launch season, culminating in the 30-day giveaway as a reward to the site's highly active and engaged members.

"Our community is what makes 1UP.com special," said Sam Kennedy, Editor- in-Chief of 1UP.com. "Our members are the lifeblood of our site-when they blog, make comments, and upload videos and game files, they elevate what we're doing from pure editorial to a shared conversation about gaming culture.

Video games: Ever more ways to play

The biggest news for the video game world this season has been the release of new consoles from Nintendo and Sony. The worst news for video game shoppers is that the new units join an already crowded aisle of gaming gifts.

There are now about 10 game consoles and portable players on the market. And that doesn't include the games themselves.

Some of the games are available for just about every system while others are "exclusive" to one machine or another. There's a version of the latest Madden NFL, for example, for everything from GameBoys to Xboxes to the new PS3. But other titles, such as a new game based on "The Sopranos," may appear only on the PlayStation 2.

Nintendo Wii sells more than 600,000 units in eight days since ...

TORONTO (CP) - Nintendo has sold more than 600,000 of its Wii video game consoles in North America since its Nov. 19 launch, the company said Tuesday.